2022

2022年

1. Metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) by Streptomyces griseolus CYP105A1 and its variants.
   Yuya Yogo, Kaori Yasuda, Teisuke Takita, Kiyoshi Yasukawa, Yuichiro Iwai, Miyu Nishikawa, Hiroshi Sugimoto, Shinichi Ikushiro, Toshiyuki Sakak
   Drug metabolism and pharmacokinetics 45 100455-100455 (2022)
   
   
2. Comparison of the stability of CYP105A1 and its variants engineered for production of active forms of vitamin D.
   Teisuke Takita, Hiro Sakuma, Ren Ohashi, Somaye Nilouyal, Sho Nemoto, Moeka Wada, Yuya Yogo,Kaori Yasuda, Shinichi Ikushiro, Toshiyuki Sakaki, Kiyoshi Yasukawa
   Bioscience, biotechnology, and biochemistry 86(4) 444-454 (2022)
   
   
3. Novel DNA Aptamer for CYP24A1 Inhibition with Enhanced Antiproliferative Activity in Cancer Cells.
   Madhu Biyani, Kaori Yasuda, Yasuhiro Isogai, Yuki Okamoto, Wei Weilin, Noriyuki Kodera, Holger Flechsig, Toshiyuki Sakaki, Miki Nakajima, Manish Biyani
   ACS applied materials & interfaces 14(16) 18064-18078(2022)
   
   
4. In Silico Prediction of the Metabolic Resistance of Vitamin D Analogs against CYP3A4 Metabolizing Enzyme.
   Teresa Żołek, Kaori Yasuda, Geoffrey Brown, Toshiyuki Sakaki, Andrzej Kutner
   International journal of molecular sciences 23(14)(2022)
   
   
5. Robust osteogenic efficacy of 2α-heteroarylalkyl vitamin D analogue AH-1 in VDR (R270L) hereditary vitamin D-dependent rickets model rats.
   Miyu Nishikawa, Naruhiro Murose, Hiroki Mano, Kaori Yasuda, Yasuhiro Isogai, Atsushi Kittaka,Masashi Takano, Shinichi Ikushiro, Toshiyuki Sakaki
   Scientific reports 12(1) 12517-12517(2022)
   
   
6. The First Convergent Synthesis of 23,23-Difluoro-25-hydroxyvitamin D3 and Its 24-Hydroxy Derivatives: Preliminary Assessment of Biological Activities
   Sayuri Mototani, Fumihiro Kawagoe, Kaori Yasuda, Hiroki Mano, Toshiyuki Sakaki, Atsushi Kittaka
   Molecules 27(16) 5352-5352(2022)
   
   
7. Development of nanoluciferase-based sensing system that can specifically detect 1α,25-dihydroxyvitamin D in living cells.
   Hiroki Mano, Takuya Kushioka, Satoko Kise, Chika Nagao, Ayano Iijima, Miyu Nishikawa, Shinichi Ikushiro, Kaori Yasuda, Sayuri Matsuoka, Toshiyuki Sakaki
   The Journal of steroid biochemistry and molecular biology 106233-106233(2022)